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Co-funded by the ANR (French National Research Agency) and the DFG (German Research Foundation), our project investigates how the communication between the endoplasmic reticulum and mitochondria, at contact sites called mitochondria-associated membranes (MAMs), influences development and recovery from metabolic dysfunction-associated steatotic liver disease (MASLD; formerly NAFLD). Our project spans in vitro approaches (in both hepatocytes and non-parenchymal cells), in vivo modelling (in mice) and a clinical trial. These are coordinated over 4 partner labs in Paris, Lyon, Munich and Lisbon. We seek to recruit 3 postdocs and 1 technical staff; each position will be based at a partner lab and will require extensive coordination and cooperation with other partner labs.

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The Munich Quantum Valley aims at developing a full quantum computing stack, from the application level to the physical quantum hardware. Within this interdisciplinary project, we are looking for a strong candidate to contribute to the development of quantum algorithms and applications, focusing on quantum walks and quantum machine learning on graph structures.

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Project Description In a DFG-funded project on infection of the liver with hepatitis B viruses, we are characterizing the immune determinants for control of infection vs failure to control of infection. The focus of the project is on virus-specific CD8 T cells and the local hepatic regulation of their effector functions through environmental and cytokine-induced signals. The AG Wohlleber is looking for a Post-doctoral researcher to investigate the regulation and dynamics of CD8 T cell immunity and identify mechanisms or pathways that will decide whether an HBV infection will develop into acute or chronic infection. Your expertise - PhD in life sciences, preferably (liver) immunology and/or viral hepatitis. - Experience in high-dimensional flow cytometry for phenotyping of immune cells and in functional assays determining T cell functions - Experience with in vivo experiments in preclinical model systems of viral infection - Excellent writing and communication skills - Experience in RNA-sequencing and bio-informatic analysis is a plus - Flexible team player We are offering excellent research conditions, a highly motivated and interdisciplinary team, a friendly working atmosphere and possibilities to further extend your qualifications through educational programs within the DFG-funded collaborative research center SFB-TRR 179. The position is available from the December 1st 2021 for 2 years, with possibility for extension. Interested candidates should send a letter of motivation, curriculum vitae and at least two reference letters (or the referees’ contact info) as a single document.

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Stellenausschreibung: Gruppenleiter/in / Post-Doc Einstellungsdatum: Zum nächstmöglichen Zeitpunkt Themengebiet – Informationsmanagement und digitale Transformation

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